Advanced Drug Formulation Design to Optimize Therapeutic Outcomes

| Pharmaceutics | 0 COMMENTS »

by III, Robert O. Williams, David R. Taft, Jason T. McConville

Advanced Drug Formulation Design to Optimize Therapeutic Outcomes demonstrates how advanced formulation designs and delivery technologies can be used to improve drug efficacy and treatment outcomes in particular therapeutic categories or disease states.

This book discusses nanoparticle systems for cancer treatments, and also presents cutting edge immono-regulation agents for transplantation and the local targeting of drugs, especially poorly water soluble drugs to provide enhanced therapeutic outcomes. In addition, it highlights areas of therapy showing the most promise for improvement in clinical outcomes via advanced formulation design.

Features

• addresses numerous advanced formulation and delivery technologies, including mucoadhesion, chronopharmaceutical delivery through smart delivery devices, targeted nanoparticle systems, and advanced solubilization technologies with liposomal delivery
• covers major therapeutic categories such as infectious disease, cancer, CNS disorders, and endocrine disorders
• includes pre-clinical or clinical evidence, showing an enhanced therapy achieved with advanced formulation design
• discusses difficult-to-treat tumors requiring chemotherapeutic agents to pass the blood brain barrier, which is of particular interest for improving the overall efficacy of such drugs with severe side-effects when administered in high doses

Partial Table of Contents

Part 1: Infectious Diseases

• Pulmonary Infections
• Oral Infections
• Systemic Infections
• Ophthalmic Infections

Part 2: Oncology

• Targeted Nanoparticle Systems for Cancer Therapy
• Systemic Delivery of Anti-cancer Agents
• Cancer and the Blood Brain Barrier

Part 3: Transplantation

• Immunosuppression for Transplantation Patients
• Systemic Delivery of Immunosuppressants
• Targeted Delivery of Immunosuppresants

Part 4: Other Therapies

• Trans-Mucosal Delivery
• CNS Diseases
• Endocrinological Diseases

Index

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